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Thiazolidinedione (TZD) compounds, such as rosiglitazone (ROSI), pioglitazone (PIO), and troglitazone (TRO), reduced the mortality of mice after GPX4 was loss by inhibiting the action of ACSL4, indicating that these compounds may show potential therapeutic effects on AKI [43, 48]

Jahan, M

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This interaction was inhibited by SO286 in a dose-dependent manner, but not by SO82 (Fig

Pharmacokinetics and bioavailability of the isoflavones formononetin and ononin and their in vitro absorption in Ussing chamber and Caco-2 cell models

Dexmedetomidine post-conditioning alleviates myocardial ischemia-reperfusion injury in rats by ferroptosis inhibition via SLC7A11/GPX4 axis activation